血红蛋白与一氧化氮的生物化学反应

周剑涛 已出版文章查询
周剑涛
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1 周思畅 已出版文章查询
周思畅
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1黄冈卫生学校生化教研室,湖北,438000

2中国药科大学,南京,210009


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血红蛋白(Hb)的血红素或HbβCys93分别与一氧化氮(NO)形成铁亚硝酰血红蛋白[Hb(FeⅡ)NO]或S-亚硝基血红蛋白(SNO-Hb).两种存在状态与Hb铁的氧化还原化学以及Hb构象有关.Hb分子内 NO能从血红素转移至βCys93巯基,调节NO的贮存与释放.

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