磁共振扩散加权成像在鉴别鼻咽癌放疗后鼻咽坏死与复发中的价值

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1350014福州 福建医科大学教学医院(福建省肿瘤医院放疗科)


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目的 评价磁共振扩散加权成像(DWI)以及表观扩散系数(ADC)值测量在鼻咽癌放疗后鼻咽坏死与复发鉴别诊断中的应用价值.方法 2008年7月至2010年12月,35例经我院治疗并经病理诊断证实的鼻咽癌放疗后鼻咽坏死和同期随机选取的35例鼻咽癌放疗后复发的患者,均接受了常规MRI检查及DWI(扩散敏感系数,即b值采用:0s/mm2及800s/mm2),分别测量放疗后鼻咽坏死灶及肿瘤复发区的ADC值,计算其平均值.结果 鼻咽坏死灶在DWI上表现为不均匀的低信号,而肿瘤复发病灶表现为高信号.鼻咽坏死组及复发组ADC平均值分别为(1.073±0.0383)×10-3mm2/s和(0.844±0.0309)×10-3 mm2/s;最大值分别为(1.728±0.0527)×10-3mm2/s和(1.477±0.0675)×10-3mm2/s.鼻咽坏死组ADC平均值及最大值均大于复发组,差异有统计学意义(t1=4.645,P<0.001t2=2.932,P<0.005).结论 DWI以及ADC值测量在鼻咽癌放疗后鼻咽坏死与复发的鉴别诊断中具有重要价值,可作为常规MR序列的重要补充.

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DOI: http://dx.doi.org/10.3969/j.issn.1674-5671.2011.04.08

语种: 中文   

基金福建省医学创新课题(2011-CX-15)

关键词鼻咽癌 坏死 复发 DWI ADC


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